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Here's what we chose for you from NEJM Group today: New England Journal of Medicine: Perspective: As difficult as 2020 was, it also brought some...

Dear Readers, This marks our final issue of Physician's First Watch. Over the past couple of weeks, hundreds of you have written to us to...

Blood pressure (BP)–lowering treatment is associated with lower risk for cardiovascular (CV) events across a wide range of BP levels and in patients with...

Higher body-mass index is associated with increased risk for severe COVID-19–related outcomes, even at a BMI considered a healthy weight, according to...

The FDA has embarked on a process to ban menthol cigarettes and all flavored cigars. In a statement released Thursday, the acting FDA commissioner, Dr...

Here's what we chose for you from NEJM Group today: NEJM Audio Interview: Firearm Regulation in Australia: Dr. Joel Negin discusses the anniversary of sweeping...

This is the fourth of four Clinical Conversations interviews on race and clinical equity in the U.S. We talk with Dr. Joseph Betancourt, an internist...

For patients with respiratory infections, delaying antibiotics could be a safe way to reduce antibiotic use, according to a study in The BMJ. Researchers analyzed...

Among hospitalized older adults with COVID-19–like illness, those who tested negative for COVID-19 were far more likely to have been vaccinated than...

See what's happening around NEJM Group: NEJM Primary Care/Hospitalist Page: Case record: A 78-year-old man was admitted with a forehead and scalp...

For many people with migraine, it can be difficult to find a treatment that is effective and reliable, and information on how medications compare to one another is lacking.

A study posted to bioRxiv reveals that the monovalent XBB.1.5 vaccine booster significantly boosts neutralizing antibodies against new SARS-CoV-2 Omicron sub-variants. The research shows that both XBB.1.5 vaccination and infection elevate neutralizing titers, with the vaccine being particularly effective in infection-naïve individuals and those previously infected with Omicron.

A 20-year Australian study has found no evidence to suggest cannabis reduces illicit opioid use, and it may not be an effective long-term method of reducing harm for those with an opioid use disorder or problematic use of opioids.

A large proportion of patients who start taking ADHD medication, especially young adults, stop within the first year.

Study reveals that pregnant women infected with COVID-19 had a higher risk of preterm delivery, with significant health and socioeconomic implications. However, early vaccination adopters showed protection from these effects, highlighting the critical role of vaccines in safeguarding future generations' health, especially in the U.S., where the study was conducted.

Scientists have discovered new antiviral compounds from a rare bacterial strain, offering a novel approach to target hepatitis B virus. These compounds work by altering membrane permeability in infected cells, leading to the release of immature viral particles, a mechanism distinct from current HBV treatments.

A research team at The Ohio State University Wexner Medical Center and College of Medicine has been approved for a $14 million award from the Patient-Centered Outcomes Research Institute (PCORI) to study whether a higher daily dose of aspirin is more effective in decreasing the risk of dangerous blood pressure complications among some pregnant people.