British Columbia Drug and Poison Information Centre (BC DPIC)

Epuris™ capsules contain isotretinoin formulated with Lidose® technology to ensure they are readily absorbed in the fasting and non-fasting state. It should not be substituted with other marketed formulations of isortretinoin. Indicated for the treatment of severe nodular and/or inflammatory acne, acne conglobata and recalcitrant acne in those patients unresponsive to conventional first-line therapies. As with all formulations of isotretinoin, it is a known teratogen and contraindicated in pregnancy. Women of child-bearing age should meet "Conditions of use" prior to starting therapy. This information is found at: www.epuris.ca/healthcare.html.