Entrectinib

Trade Name: 
Rozlytrek
Manufacturer/Distributor: 
Hoffman-La Roche Limited
Classification: 
Antineoplastic agent
ATC Class: 
L01EX14 - entrectinib
Status: 
active
Presentation: 
Capsule: 100 mg. DIN: 02495007
Capsule: 200 mg. DIN: 02495015
Comments: 
A NOC/c has been issued. Used for the treatment of adult patients with unresectable locally advanced or metastatic extracranial solid tumours, including brain metastases, that have a neurotrophic tyrosine receptor kinase (NTRK) gene fusion without a known acquired resistance mutation, and with no satisfactory treatment options.