EurekAlert! - Medicine and Health

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Updated: 1 day 5 hours ago

Genestack signs multi-year agreement with AstraZeneca to implement Omics Data Manager

Thu, 2020-05-28 21:00
(Genestack Ltd) Genestack Ltd. today announced that its flagship multi-omics data catalogue, curation and integrative search product, Omics Data Manager (ODM), has been licensed and implemented by AstraZeneca. Genestack's ODM is an enabling technology providing a central hub for organizing and querying multi-omics data from multiple sites, including transcriptomics and proteomics. ODM provides mission-critical technology modules that enable life science enterprises to execute their data strategy.
Categories: News

New gut-brain link: How gut mucus could help treat brain disorders

Thu, 2020-05-28 21:00
(RMIT University) Gut bacterial imbalance is linked with many neurological disorders. Now researchers have identified a common thread: changes in gut mucus. It's a new gut-brain connection that opens fresh paths for scientists searching for ways to treat brain disorders by targeting our 'second brain' - the gut.
Categories: News

Nilotinib appears safe and affects biomarkers in Alzheimer's disease clinical trial

Thu, 2020-05-28 21:00
(Georgetown University Medical Center) A Georgetown University Medical Center clinical trial investigating the cancer drug nilotinib in people with Alzheimer's disease finds that it is safe and well-tolerated, and researchers say the drug should be tested in a larger study to further determine its safety and efficacy as a potential disease-modifying strategy.
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A roadmap for effective treatment of COVID-19

Thu, 2020-05-28 21:00
(Frontiers) Researchers from the US Food and Drug Administration have reviewed the available scientific literature on COVID-19 and systematically outlined key immunological factors underlying COVID-19 disease severity. Based on these factors, the researchers indicate a range of approved and available drugs, as well as drugs currently under clinical investigation, as possible candidates for treatment.
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SwRI awarded $1.9 million to develop treatment for COVID-19 in collaboration with DOD

Wed, 2020-05-27 21:00
(Southwest Research Institute) Using Department of Defense supercomputers, Southwest Research Institute is virtually screening millions of drug compounds to search for and test possible treatment options for the novel coronavirus 2019. The Henry M. Jackson Foundation for the Advancement of Military Medicine Inc. (HJF) has awarded SwRI a $1.9 million, one-year contract to support these efforts to identify potential COVID-19 treatments. HJF supports COVID-19 countermeasure development at the Walter Reed Army Institute of Research.
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Researchers in Brazil develop low-cost mechanical ventilators

Wed, 2020-05-27 21:00
(Fundação de Amparo à Pesquisa do Estado de São Paulo) Created at the University of São Paulo's Engineering School (POLI-USP), the machine costs approximately 7% as much as a conventional ventilator and can be freely manufactured by companies that obtain approval from the national health surveillance authority.
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CMSC annual meeting virtual exhibits, mini poster session and product theaters scheduled for June 1-14

Wed, 2020-05-27 21:00
(Consortium of MS Centers) The Consortium of Multiple Sclerosis Centers (CMSC) announces a state-of-the-art virtual experience for healthcare professionals to learn about the latest products, innovations and services from industry supporters and partners to optimize MS care. Scheduled for June 1-14, 2020, the CMSC Virtual Exhibits experience will also include Product Theaters and a Mini Poster Session of the latest MS research and discoveries.
Categories: News

PSA screening: Benefit does not outweigh harm

Wed, 2020-05-27 21:00
(Institute for Quality and Efficiency in Health Care) PSA screening: benefit does not outweigh harmSome men benefit from an earlier cancer diagnosis. However, more men are at risk of overdiagnosis and treatment-related complications.
Categories: News

Reusable face mask could be answer to PPE shortfall

Wed, 2020-05-27 21:00
(University of Cincinnati) Engineers at the University of Cincinnati are using a National Science Foundation grant to develop a face mask that can be sterilized with heat for re-use.
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Study finds surge in hydroxychloroquine/chloroquine prescriptions during COVID-19

Wed, 2020-05-27 21:00
(Brigham and Women's Hospital) A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic.
Categories: News

Gold mining with mercury poses health threats for miles downstream

Wed, 2020-05-27 21:00
(Duke University) Small-scale gold mining in the Peruvian Amazon poses a health hazard not only to the miners and communities near where mercury is used to extract gold from ore, but also to downstream communities hundreds of kilometers away where people eat mercury-contaminated river fish as part of their diet. Downstream children under 12 with the highest levels of mercury in their bodies were found to have lost IQ points and become anemic.
Categories: News

Heart surgery stalled as COVID-19 spread

Wed, 2020-05-27 21:00
(University of Ottawa) In two recent journal articles, Dr. Marc Ruel explores how hospitals worldwide scaled back on heart surgeries as the pandemic hit, and how they can resume those operations in a world still plagued by the SARS-CoV-2 virus.
Categories: News

Breaking up is hard to do (especially for sex chromosomes)

Wed, 2020-05-27 21:00
(Memorial Sloan Kettering Cancer Center) A team of scientists at the Sloan Kettering Institute has discovered how the X and Y chromosomes find one another, break, and recombine during meiosis even though they have little in common.
Categories: News

Cancer drugs cause large cells that resist treatment; scientist aims to stop it

Wed, 2020-05-27 21:00
(University of Texas Health Science Center at San Antonio) Fueled by genetic changes due to cancer therapy itself, rogue cells may become very large with twice or quadruple the number of chromosomes found in healthy cells. Dr. Daruka Mahadevan of the Mays Cancer Center, home to UT Health San Antonio MD Anderson, seeks to find drugs that prevent or treat this problem.
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Blocking tumor signals can hinder cancer's spread

Wed, 2020-05-27 21:00
(University of Pennsylvania) A University of Pennsylvania-led team used an inhibitor of an enzyme called p38α kinase to suppress the spread of melanoma to the lungs in a mouse model.
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CT findings of coronavirus disease (COVID-19) in children 'often negative'

Wed, 2020-05-27 21:00
(American Roentgen Ray Society) The newest article in the American Journal of Roentgenology's open-access COVID-19 collection revealed a high frequency (77%) of negative chest CT findings among pediatric patients (n=30; 10 months-18 years) with COVID-19, while also suggesting that bilateral, lower lobe-predominant ground-glass opacities are common in the subset of children with positive CT findings. Consistent with reported symptomatology in children, the authors of this AJR article also observed a correlation between increasing age and increasing severity of findings.
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Modelling predicts COVID-19 resurgence if physical distancing relaxed

Wed, 2020-05-27 21:00
(University of Guelph) If physical distancing measures are relaxed too much or too quickly, Ontario could see hospitals overwhelmed with COVID-19 patients as well as exponential growth in deaths, concludes new University of Guelph research.
Categories: News

Carfilzomib does not improve outcomes in newly diagnosed myeloma compared to bortezomib

Wed, 2020-05-27 21:00
(ECOG-ACRIN Cancer Research Group) The combination of carfilzomib, lenalidomide, and dexamethasone (KRd) did not improve progression-free survival in patients with newly diagnosed myeloma absent a high-risk disease prognosis, compared with the standard of care -- bortezomib, lenalidomide, and dexamethasone (VRd). The data from a planned interim analysis for the ENDURANCE (E1A11) randomized phase three trial will be presented at the ASCO 2020 plenary. KRd had more severe cardiac, pulmonary, and renal toxicities. Neuropathy was more common among those receiving VRd.
Categories: News

Researchers find CBD improves arthritis symptoms in dogs

Wed, 2020-05-27 21:00
(Baylor College of Medicine) This study shows that in dogs diagnosed with arthritis, CBD treatment significantly improved quality of life as documented by both owner and veterinarian assessments.
Categories: News

Surgery and radiation do not extend survival in newly diagnosed metastatic breast cancer

Wed, 2020-05-27 21:00
(ECOG-ACRIN Cancer Research Group) Women who present with a new diagnosis of breast cancer that is already in an advanced stage (stage IV) face questions about having surgery and radiation to the tumor in the breast (local therapy). Based on the results of the long-awaited E2108 randomized phase 3 trial at #ASCO20, these women should not be offered surgery and radiation for the primary breast tumor with the expectation of a survival benefit.
Categories: News