Naproxen + Esomeprazole

Trade Name:

Vimovo

Manufacturer/Distributor:

AstraZeneca

www.astrazeneca.ca ; Medical Information 1-800-668-6000

Classification:

NSAID + PPI

ATC Class:

M01AE52 - naproxen and esomprazole

Status:

active

Notice of Compliance (yyyy/mm/dd):

2011/01/13

Date Marketed in Canada (yyyy/mm/dd):

2011/01/14

Presentation:

Tablet: 375 mg naproxen + 20 mg esomeprazole. DIN: 02361701

Tablet: 500 mg naproxen + 20 mg esomeprazole. DIN: 02361728

Comments:

For treatment of signs and symptoms in patients with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis and to decrease the risk of developing gastric ulcers in patients at risk for developing NSAID-associated gastric ulcers. The tablets contain an enteric-coated naproxen core and immediate-release esomeprazole film coat. The formulation is designed to release the active ingredients in a sequential manner: esomeprazole is rapidly released in the stomach, followed by the delayed release of naproxen in the small intestine.

Keywords:

naproxen

Keywords:

esomeprazole

Keywords:

arthritis: rheumatoid

Keywords:

osteoarthritis

Keywords:

spondylitis: ankylosing

Access:

public

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Heparin Sodium	Hepalean	Heparin anticoagulant
Estropipate	Ogen
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Cilazapril	Inhibace	ACE inhibitor
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Risedronate + Calcium carbonate	Actonel APC
Lenalidomide	Revlimid	Antineoplastic agent
Midodrine	Amantine	Alpha adrenergic agonist
Norgestrel + ethinyl estradiol	Ovral	Oral contraceptive
Ethinyl estradiol + norgestrel	Ovral	Oral contraceptive
Propoxyphene	Darvon-N; 642	Narcotic
Sitaxsentan	Thelin	Endothelin receptor antagonist
Lithium, sustained release	Lithmax	Antimanic agents
Aluminum chloride hexahydrate	Hydrosal gel	Antiperspirant
Probenecid	Benuryl	Uricosuric agent
Digoxin Immune Fab (Ovine)	Digibind	Antidote
Tetracaine	Pontocaine (spinal anesthesia)	Local anesthetic
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Oxybutynin	Uromax	Urinary Antispasmodic
Hydromorphone	Dilaudid injection; Dilaudid HP injection	Narcotic
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Calcitonin salmon nasal spray	Miacalcin NS, Sandoz Calcitonin NS, Apo-Calcitonin NS	Bone metabolism regulator
ASA + Meprobamate + Codeine + Caffeine	282 MEP	Narcotic analgesic
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Hydrocodone resin with phenyltoloxamine	Tussionex tablets	Narcotic
Metronidazole with nystatin vaginal cream	Flagystatin vaginal cream
Zafirlukast	Accolate	Leukotriene modifier for asthma
Clofedanol	Ulone	Antitussive
Ulipristal	Fibristal	Selective progesterone receptor modulator (SERM)
Tepotinib	Tepmetko	Protein kinase inibitor (antineoplastic agent)
Entrectinib	Rozlytrek	Antineoplastic agent